Methotrexate
Methotrexate is an antifolate drug used in chemotherapy. Its action is to bind dihydrofolate reductase.
It is indicated for the treatment of various malignancies at high dose and for the treatment of psoriasis and rheumatoid arthritis as a titrated weekly dose (1).
The summary of product characteristics should be consulted before prescribing this drug.
Reference:
- (1) Current Problems in Pharmacovigilance (2000), 26, 10.
Related pages
- Side effects
- Action plan for side effects
- Monitoring rheumatological disease
- Interactions
- Monitoring for safety
- Methotrexate in rheumatoid arthritis
- Methotrexate in therapeutic abortion
- Methotrexate in Crohn's disease and ulcerative colitis
- Folate
- N-terminal propeptide of procollagen type III (PIIINP) and methotrexate
- Using folic acid with methotrexate in rheumatoid arthritis
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