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Methotrexate in therapeutic abortion

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Methotrexate has been used in conjunction with misoprostol for therapeutic abortions:

  • abortions with mifepristone and misoprostol were completed faster than those with methotrexate, but overall success rate, adverse effects, and complications were similar (1)


  1. Royal college of obstetricians and gynaecologists (RCOG) 2011. The care of women requesting induced abortion. Evidence based clinical guideline number 7.

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