This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Side effects

Authoring team

A possible side effect is the development of pulmonary fibrosis - the changes induced by the drug may resolve despite continuing treatment.

Other side effects include:

  • impairment of liver function
  • bone marrow suppression
  • pneumonitis
  • megaloblastic anaemia
  • nausea, vomiting and anorexia
  • impaired fertility, menstrual dysfunction and amenorrhoea, oligospermia
  • teratogenic - should not be used in pregnancy, and conception should be avoided for at least 3 months after treatment with methotrexate
  • skin ulceration in psoriatic patients and rarely painful erosion of psoriatic plaques have been reported (1)

The summary of product characteristics must be consulted before prescribing this drug.

Reference:

  • Wyeth (February 2001). Methotrexate injection 25mg/ml and methotrexate 2.5mg tablets. Summary of Product Characteristics and Data Sheet.

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.