This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Jaundice with a obstructive biochemical profile

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Cholestasis is defined as failure of normal amounts of bile to reach the duodenum. The source of the interference may reside in the main bile ducts - extrahepatic cholestasis - or within the liver - intrahepatic cholestasis.

Morphologically, cholestasis is characterised by the accumulation of bile in liver cells and biliary passages; biochemically, by the retention of all substances normally excreted in the bile.

Presentation is usually with pruritus and the slow onset of jaundice.

The term "obstructive jaundice" usually refers to cholestasis of extra-hepatic origin.

Related pages

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.