This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Management

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

General management:

  • nutrition - problem is that of intestinal bile salt deficiency:
    • calorie and protein intake must be maintained but fat reduced. Additional fat supplied by medium chain triglycerides e.g. Portagen or coconut oil
    • fat soluble vitamins - A, D, E, K - may need to be supplemented if signs of deficiency
  • pruritus - options:
    • external biliary drainage
    • cholestyramine
    • phototherapy
    • ursodeoxycholic acid
    • rifampicin
  • hepatic osteodystrophy may require vitamin D, phosphate or calcium; oestrogens in postmenopausal women

Extrahepatic cholestasis often requires surgical management.

Note that the use of clofibrate therapy in the hyperlipidaemia associated of cholestasis is associated with a raised serum cholesterol.

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.