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Skeletal disorders

Authoring team

The commonest skeletal disorder is dysostosis multiplex:

  • bone formation is abnormal in the metaphysis, diaphysis and epiphysis
  • radiographs demonstrate:
    • oar shaped ribs - the flattened end at the sternum
    • enlarged diaphyses and roughened epiphysial centres
    • anterior beaking of the vertebrae
    • odontoid hypoplasia
    • rarely, spinal dislocation

Patients, notably with Gaucher's disease, may suffer vascular damage to bone such as avascular necrosis of the femoral head.

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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