If intermediate probability of asthma

Intermediate Probability:

Adults and children who have some, but not all, of the typical features of asthma on an initial structured clinical assessment or who do not respond well to a monitored initiation of treatment have an intermediate probability of asthma

Spirometry, with bronchodilator reversibility as appropriate, is the preferred initial test for investigating intermediate probability of asthma in adults, and in children old enough to produce reliable results on testing.

• In adults and children with an intermediate probability of asthma and airways obstruction identified through spirometry, undertake reversibility tests and/or a monitored initiation of treatment assessing the response to treatment by repeating lung function tests and objective measures of asthma control
  
  
• In adults and children with an intermediate probability of asthma and normal spirometry results, undertake challenge tests and/or measurement of FeNO to identify eosinophilic inflammation
  
  
• In children with an intermediate probability of asthma who cannot perform spirometry:
  • consider watchful waiting if the child is asymptomatic
  • offer a carefully monitored trial of treatment if the child is symptomatic.

Check for possible occupational asthma by asking employed people with suspected new-onset asthma, or established asthma that is poorly controlled:

• are symptoms better on days away from work?
• are symptoms better when on holiday?

Make sure all answers are recorded for later review (2).

Open Image in Modal

Reference:

• (1) British Thoracic Society (BTS)/Scottish Intercollegiate Guidelines Network (SIGN) 2019. British Guideline on the Management of Asthma. A national clinical guideline
• (2) National Institute for Health and Clinical Excellence (NICE) 2017 Asthma: diagnosis, monitoring and chronic asthma management