This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Investigation

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The systemic auto-antibodies and inflammatory markers are normal.

The chest radiograph is normal which should help distinguish cases of neurosarcoid and Churg-Strauss vasculitis.

MRI scanning of the brain reveals:

  • multiple white matter lesions
  • multiple cortical lesions
  • occasionally there may be large areas of high signal

The cerebrospinal fluid may show:

  • elevated protein
  • lymphocyte pleocytosis

Cerebral angiography may show:

  • irregular narrowing of intracranial arteries
  • blunt-ending of intracranial arteries

Brain biopsy shows:

  • inflammation of small arteries (100-500 microns)
  • lymphocyte infiltration
  • small numbers of giant cells
  • thrombosis of vessels corresponds to infarcted areas
  • there is variable meningeal involvement

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.