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Small intestinal Crohn's

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The affects of Crohn's disease on the small intestine include:

  • mouth ulcers:
    • apthous ulcers are common in active disease
    • rarely, there are oropharyngeal Crohn's ulcers
  • duodenal Crohn's ulcers:
    • these are usually postbulbar and are very rare
    • associated with a high ESR
  • fibrotic stricture is suggested by colicky abdominal pain without systemic illness or localised tenderness
  • malabsorption:
    • rarely occurs unless there is widespread disease
    • malabsorption of vitamin B12 will occur if 80cm or more of the distal ileum is diseased
    • protein enteropathy rarely results in widespread oedema
  • small intestinal disease will often be accompanied by an abdominal mass, most often in the right iliac fossa and doughy in consistency
  • extraintestinal manifestations are rarer with small intestinal than with colonic Crohn's disease

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