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Features of androgenic alopecia in men

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Male androgenic alopecia, also known as male pattern baldness is an androgen dependent disorder seen in genetically predisposed individuals (1).

Male AGA is seen in all ethnicities

  • the highest prevalence is seen amongst the Caucasians with around 80% of men aged over 70 years having AGA
  • in Asians the reported prevalence is 47-60% in males older than 70 years
  • older studies report that balding in African-American men is four times less common than compared to Caucasians (2)

The frequency and severity increases with age in every population (2)

Genetic factors predisposes to AGA

  • the current scientific data suggest that AGA is a polygenic disorder
  • there are strong concordance rates of between 80% and 90% for monozygotic twins
  • risk of developing AGA is greatly increased in men with a father suffering from AGA than in men with a non-balding father (2)

Although AGA is androgen dependant, almost all men with AGA have a normal circulating androgen level

  • it is thought to be due to increased androgen receptor density and/or increased activity of 5-alpha-reductase type II in genetically predisposed hair follicles (2)

Reference:


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