This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Tryptase

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Tryptase is the predominant protein in mast cell granules and cleaves proteins at arginine and lysine residues.

  • stored and released from mast cell granules upon activation
  • mast cells are found in many tissues but are present in greater numbers along epithelial linings of the body, such as the skin, respiratory tract and gastrointestinal tract, as well as the perivascular tissue surrounding blood vessels
    • involved in a variety of physiological and pathophysiological states, including immediate hypersensitivity, delayed-type hypersensitivity, cell growth regulation, defense against neoplasia, and pain and itch sensation
  • elevated levels of serum tryptase occur in both anaphylactic and anaphylactoid reactions
    • however a negative test does not exclude anaphylaxis

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.