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Aetiology of ischaemic heart disease

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

The vast majority of ischaemic heart disease is caused by coronary artery atherosclerosis.

Rarer causes of ischaemic heart disease include:

  • arteritides:
    • systemic lupus erythematosus
    • polyarteritis nodosa
    • syphilis
    • Takayasu's arteritis
    • rheumatoid arthritis
    • ankylosing spondylitis

  • embolism:
    • infective endocarditis
    • left heart thrombus or tumour
    • prosthetic valve thrombus
    • cardiac catheterisation
    • paradoxical embolism

  • coronary artery wall thickening:
    • amyloidosis
    • radiation therapy
    • Hurler's disease
    • pseudoxanthoma elasticum

  • aortic dissection causing coronary dissection

  • coronary spasm

  • congenital arterial disease:
    • anomalous derivation of coronary arteries from the pulmonary artery
    • arteriovenous fistula

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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