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Gout is considered a progressive disease which will eventually end up as severe tophaceous gout (with joint damage and significant functional impairment) in the absence of effective long-term therapy (1).

The disease is commonly divided into the following phases:

  • initial asymptomatic hyperuricaemia
  • recurrent acute gout  attacks interspersed with asymptomatic intercritical periods
  • chronic symptomatic tophaceous gout (with inadequately treated hyperuricemia) (1).


  • it should be noted that these are not discrete phases but a continuum (1).


Last reviewed 07/2021