acute myocardial infarction - the rise in CRP appears within 24-48 hrs. The level begins to fall by the third day and becomes negative after 1-2 weeks. The rise of CRP correlates with peak CK-MB levels but CRP occurs 1-3 days later. If the CRP remains high then this indicates tissue damage in the heart or elsewhere. CRP is not raised in angina, if there is no tissue damage
infarction of other tissues
rejection of kidney or marrow transplant
malignancy, especially lung, colon, breast
following surgery - usually begins to rise within 4-6 hrs to peak at 48-72 hrs. The failure to fall indicates possible infection
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