This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

CK in myocardial disease

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

CK frequently rises following myocardial infarction and in myocarditis. It may also rise as a result of intervention: coronary angiography and angioplasty, external cardiac massage and DC cardioversion.

Following myocardial infarction:

  • total CK: peak value 18-30 hrs; duration 2-5 days; level 5-10 times normal
  • CK-MB: peak value 12-24 hrs; duration 1.5-3 days; level variably raised

Note:

  • the rise in CK is proportional to the extent of infarction
  • total CK is 98% sensitive but only 65-85% specific for acute myocardial infarction; CK-MB is more specific
  • prolonged elevations of total CK may represent surgery or infarction. Differentiation of infarction from surgery, particularly cardiac surgery, post-operatively is difficult: total CK and CK-MB rises occur earlier and are smaller for infarction
  • repeated infarction may be indicated by a total CK plateau and independent peaks of CK-MB. The latter has a shorter half-life

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.