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Clinical features

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

There are the usual clinical features of hypocalcaemia:

  • carpopedal spasm
  • paraesthesiae
  • abdominal cramps
  • papilloedema
  • epilepsy

Associated endocrine disorders include:

  • hypothyroidism
  • diabetes mellitus

Phenotypically pseudohypoparathyroidism is associated with:

  • short stature
  • mental retardation
  • obesity
  • strabismus
  • subcutaneous calcification - rare in acquired hypoparathyroidism
  • shortened metacarpals and metatarsals:
    • brachydactyly
    • especially 3rd, 4th and 5th rays
  • bowing of the legs
  • rounded moon face
  • cerebral calcification

Metacarpal shortening may easily be demonstrated by asking the patient to make a fist and observing that the relevant knuckles are absent.


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