This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Treatment

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Seek expert advice.

Supportive treatment, including administering angiotensin-receptor blockers (ARBs) and salt restriction, should be administered to all IgAN patients (1)

  • importance of conservative therapy to reduce proteinuria and slow the rate of renal function decline in IgAN cannot be overemphasized (2)

A low protein diet is also advisable in nephrotic IgA nephropathy patients (1)

If recurrent chronic tonsillar infections then tonsillectomy is indicated

Use of immune-suppressive agents depends mainly upon the progression rate, comorbidities, and histopathological changes of the kidney biopsy (1):

  • corticosteroids are currently the cornerstone of IgA nephropathy
    • NICE have stated that
      • Targeted-release budesonide is recommended as an option for treating primary immunoglobulin A nephropathy (IgAN) when there is a risk of rapid disease progression in adults with a urine protein-to-creatinine ratio of 1.5 g/g or more (3)

it is an add-on to optimised standard care including the highest tolerated licensed dose of angiotensin-converting enzyme (ACE) inhibitors or angiotensin-receptor blockers (ARBs), unless these are contraindicated

  • different therapeutic agents such as calcineurin inhibitors (CNIs), cyclophosphamide, mycophenolate mofetil, rituximab, and leflunomide (LEF) are used, but none is approved as a single or combined effective therapy for IgA nephropathy

Reference:


Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.