This site is intended for healthcare professionals

account_circleSign in
Go to /sign-in page

You can view 5 more pages before signing in

Pyrazinamide

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

This is the only bactericidal drug which is active against the intracellular forms of Mycobacterium tuberculosis. It is particularly useful in the treatment of tuberculous meningitis because of its good penetration of the blood- brain barrier.

Indications:

  • tuberculosis

Cautions:

  • gout
  • diabetes
  • beware interactions
  • impaired renal function

Contra-indications:

  • liver damage
  • porphyria

Side-effects:

  • nausea and vomiting
  • arthralgia
  • hepatomegaly
  • jaundice
  • hepatotoxicity including fever and anorexia
  • liver failure
  • sideroblastic anaemia
  • urticaria

Routes of administration:

  • oral

The summary of product characteristics should be consulted before prescribing this drug.

Related pages

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.