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Meningitis (meningococcal killed vaccine)

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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quadrivalent (ACWY) polysaccharide vaccine

  • this polysaccharide (non-conjugated) vaccine is made from the outer capsules of serogroup group A,C,W135 and Y Neisseria meningitidis organisms
  • meningococcal vaccine is a purified, heat stable, lyophilised extract from outer capsule of meningococcus serogroups A, C, Y and W135
  • in teenagers, both vaccines produce high levels of bactericidal antibodies to all four serogroups
  • response to MenC is good, regardless of the MenC vaccine received as a child
  • confers no protection against group B organisms
  • this vaccine is recommended for travellers to some countries

Check uptodate details in the The Green Book before prescribing/administering a quadrivalent (ACWY) polysaccharide vaccine.

Check the Summary of Product Characteristics (SPC) before prescribing/administering a quadrivalent (ACWY) polysaccharide vaccine.

Reference:

  1. Immunisation Against Infectious Disease - "The Green Book".Chapter 22 meningococcal (April 2019)

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