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This may be the result of pituitary acidophil cell hypersecretion.

When this condition occurs in childhood then there is stimulation of epiphyseal growth. Patients are excessively tall; and often there is associated sexual immaturity and mental retardation.

Slipping of the upper femoral epiphysis may occur.

Gigantism may rarely be seen in other conditions such as sclerosteosis

Last reviewed 01/2018