Last reviewed dd mmm yyyy. Last edited dd mmm yyyy
Botulinum toxin type A injections into the urethral sphincter for idiopathic chronic non-obstructive urinary retention
NICE state that:
The effect of botulinum toxin type A on urethral striated muscle is thought to block the presynaptic release of acetylcholine in the neuromuscular junction and subsequently achieve a chemical sphincterotomy, which is believed to relieve the rethral sphincter dysfunction (USD) and improve voiding dysfunction (VD) (2)
Reference:
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