This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Free fatty acids

Authoring team

Fatty acids are organic acids which are a defining constituents of fats. They are made up of a long, unbranched hydrocarbon chain with an even number of carbon atoms. Fatty acids may be saturated or unsaturated, essential or non-essential.

Fatty acids are absorbed from the diet directly, within the hydrophobic interior of micelles. They may result from the action of lipases on triglycerides. Once taken up by the epithelial cells of the jejunum, short chain fatty acids pass directly into the portal circulation, whereas long chain fatty acids are converted into triglyceride which passes into lymphatics within micelles.

The hydrolysis of body stores of triglyceride by a lipase enzyme produces free fatty acid and diglyceride. This step is rate-limiting and is hormonally controlled.

Effects of free fatty acids are as follows:

  • provide energy by oxidation
  • high levels of free fatty acids inhibit glycolysis and favour glycogenesis
  • inhibits hexose monophosphate shunt

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.