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GTN in the treatment of anal fissure

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • the use of GTN ointment in the treatment of chronic anal fissure has widely been accepted as efficacious
    • this treatment provides relief of painful symptoms with little long-term risk of impairment of faecal continence (1)

  • treatment with topical GTN ointment may cause unpleasant side effects e.g. headaches


  • EBM (1999), 4 (6), 174-175.

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