Treatment of staphylococcal pneumonia
Antibiotic treatment should be started after blood and sputum has been taken for culture. Initial therapy is often blind.
Consult with a bacteriologist about appropriate drug treatment if in doubt:
- penicillin-sensitive
- first choice: amoxicillin
- alternative: doxycycline or clarithromycin
- penicillinase producing
- first choice: flucloxacillin
- alternative: dependent on local sensitivities
Treatment for staphylococcal pneumonia may be with flucloxacillin 250 mg 4 times daily by mouth or IV until improvement. In severe infections, doses may be doubled.
Pneumonia (community-acquired): antimicrobial prescribing. NICE guideline [NG138]Published: 16 September 2019
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