Management of pleural effusion should be aimed at identifying the aetiology and treatment of the underlying disease.
If a transudative effusion is identified, treatment of the underlying cause will usually resolve the effusion.
Exudative effusions often require removal of fluid to relieve symptoms. This can be achieved through:
Pleurodesis is used for management of recurrent malignant effusions
Pleurectomy may be considered in exceptional cases e.g. - specially in mesothelima and in patients in good general condition with pleurodesis failure (3)
Intrapleural fibrinolytic therapy - a systematic review stated " with complicated infective pleural effusion or empyema, intrapleural fibrinolytic therapy was associated with a reduction in the requirement for surgical intervention and overall treatment failure but with no evidence of change in mortality" (4)
Reference:
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