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Mayer - Rokitansky - Küster - Hauser (MRKH) syndrome

Authoring team

  • Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome is characterized by congenital agenesis of vagina, a rudimentary uterus and normal fallopian tubes and ovaries
  • the definitive risk of benign and malignant neoplasms development in uterine remnants and ovaries in patients with MRKH syndrome is still unknown
  • there have been case reports of ovarian cancer, endodermal sinus tumor of the ovary and immature teratoma that have been associated with MRKH
  • a case report of a dysgerminoma associated with MRKH has been described (1)

Reference:

  1. Mishina A et al. Ovarian dysgerminoma in Mayer-Rokitansky-Kuster-Hauser syndrome. Eur J Obstet Gynecol Reprod Biol. 2007 Mar;131(1):105-6.

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