Clinical features
Allergic bronchopulmonary aspergillosis is characterised by wheezing, cough, and dyspnoea, along with radiographic findings of transient or “fleeting” pulmonary infiltrates and central bronchiectasis. Expectoration of thick, brownish mucus plugs is a classic feature and should raise strong clinical suspicion.
In advanced disease, digital clubbing, cyanosis, or features of cor pulmonale (peripheral oedema, splitting of the second heart sound, left parasternal or subxiphoid heave, ascites, hepatojugular reflux, and pulsatile liver) may be present.
A chest X-ray may show visible infiltrates, commonly involving the upper or middle lobe. There is raised IgE and an eosinophilia.
Reference
- Roboubi A et al. Allergic bronchopulmonary aspergillosis: A multidisciplinary review. J Mycol Med. 2023 Aug;33(3):101392
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