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Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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The condition is characterised by oedema and a reduced thickness of the dermis with with closer approximation of the subcutaneous fat to the epidermis than normal. Initially, there is degeneration of the collagen but later, it is increased. Endarteritis and minor inflammation may be found around dermal blood vessels. Skin appendages are usually unaffected in contrast to morphoea.

Progressive fibrosis is the main feature of visceral involvement.

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