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Complications with respect to stage of CKD

Authoring team

 

Common complications of the different stages of kidney disease (1):

Stage 1 (GFR > 90 mL/min/1.73 m2 with other evidence of kidney damage)

in patients with stage 1 CKD - hypertension more frequent than amongst patients without CKD

Stage 2 (GFR 60-89 mL/min/1.73 m2 ) with other evidence of kidney damage

hypertension frequent in patients with stage 2 CKD

mild elevation of parathyroid hormone

Stage 3 (GFR 30-59 mL/min/1.73 m2 )

hypertension common

decreased calcium absorption

reduced phosphate excretion

more marked elevation of parathyroid hormone

altered lipoprotein metabolism

reduced spontaneous protein intake

renal anaemia

left ventricular hypertrophy

Stage 4 (GFR 15-29 mL/min/1.73 m2)

As above but more pronounced plus -

metabolic acidosis

hyperkalaemia

decreased libido

Stage 5 (GFR 0-14 mL/min/1.73 m2 )

All the above (with greater severity) plus -

salt and water retention causing apparent heart failure anorexia

vomiting pruritus (itching without skin disease)

 

Reference:

  1. The Renal Association (May 2006).UK CKD Guidelines

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