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Epidemiology

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Approximately 4-7 million individuals are affected in the world and account for 7% to 15% of patients on renal replacement therapy (1)

It accounts for about 10% of people on dialysis. Annual incidence rates of end-stage kidney disease (ESKD) caused by ADPKD are between 6-8 per million per year in Europe (2)

Females are more likely to be diagnosed during early adulthood than males, possibly due to the use of abdominal ultrasound during pregnancy (3)

 

Reference:

  1. Mahboob M et al. Autosomal Dominant Polycystic Kidney Disease. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan.
  2. Torres VE, Harris PC, Pirson Y. Autosomal dominant polycystic kidney disease. Lancet. 2007 Apr 14;369(9569):1287-301.
  3. Willey C, Kamat S, Stellhorn R, et al. Analysis of nationwide data to determine the incidence and diagnosed prevalence of autosomal dominant polycystic kidney disease in the USA: 2013-2015. Kidney Dis (Basel). 2019 Mar;5(2):107-17.

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