Switching antidepressant (mirtazapine to moclobemide) in adults
Mirtazapine to moclobemide
Taper, washout and switch
- gradually reduce the dose of mirtazapine and stop; wait 7 days before starting moclobemide
- cross-tapering is not recommended due to the high risk of serotonin syndrome.
Reference:
- NHS Specialist Pharmacy Service (February 2023).Mirtazapine to other antidepressants: switching in adults
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