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Use of hydrocortisone in anaphylactic shock

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • hydrocortisone (as sodium succinate) should be administered after severe anaphylactic attacks to help avert late sequelae. This is of particular importance for asthmatics (who are at increased risk of severe or fatal anaphylaxis) if they have been treated with corticosteroids previously. The dose of hydrocortisone should be given by slow intravenous or intramuscular injection - care being taken to avoid inducing further hypotension.
  • hydrocortisone should be injectede slowly intravenously or intramuscularly, taking care to avoid inducing further hypotension.
  • the dose of hydrocortisone for adults and children depending on their age:
    • >12 years and adults: 200 mg IM or IV slowly
    • >6 – 12 years: 100 mg IM or IV slowly
    • >6 months – 6 years: 50 mg IM or IV slowly
    • <6 months: 25 mg IM or IV slowly


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