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Hirschsprung's disease

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Hirschsprung's disease is caused by a developmental failure of the parasympathetic plexuses of Auerbach and Meissner in the gut, leading to constipation and gut dilation.

It is a condition that usually manifests itself in the immediate neonatal period by the failure of passage of meconium followed by obstructive constipation. In some instances, when only a small segment of the rectum is affected, the build up of pressure may permit the occasional passage of stools, even intermittent bouts of diarrhoea.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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