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Chloramphenicol topical treatment and agranulocytosis

Authoring team

  • the evidence of a causal relationship between the use of topical chloramphenicol and agranulocytosis is not compelling (1,2)

Reference:

  • (1) Doon M, Walsh JB (1995). Use of chloramphenicol as a topical eye medication, time to cry a halt?. BMJ, 310, 12178.
  • (2) Walker S et al (1998). Lack of evidence of toxicity following topical chloramphenicol use. Eye, 12, 8759.

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