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Argyll-Robertson reaction

Authoring team

The Argyll Robertson reaction is the failure to constrict to light with a retention of the response to near - it is also termed the light-near dissociation. It is encountered in:

  • Argyll-Robertson pupil
  • Adie's syndrome
  • meningitis
  • alcoholism
  • tectal lesions, e.g. pinealoma
  • mesencephalon lesions
  • thalmic lesions

The lesion is presumably near the pre-tectal nucleus where the pupillary fibres from the optic tract run to enter the Edinger Westphal nucleus from the dorsal aspect. The fibres for the accommodative pupillary response come from the occipital lobe via the internal capsule and enter the Edinger Westphal nucleus along a deeper course.


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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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