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Amiodarone in atrial fibrillation

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Amiodarone is reserved for patients with atrial fibrillation who are refractory to other forms of treatment.

Amiodarone is effective in atrial fibrillation and the low doses that are often required (200 mg/day) mean that side- effects are rare.

Amiodarone is effective in converting atrial fibrillation to sinus rhythm and maintaining sinus rhythm. Symptom control is good if breakthrough attacks occur.

The use of amiodarone in atrial fibrillation may interact with two commonly used drugs:

  • digoxin: resulting in increased plasma concentrations of digoxin
  • warfarin: resulting in overanticoagulation

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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