Carcinomas are renowned for metastasising to local lymph nodes, but this may also be the route of sarcomas. Dissemination follows the natural route of lymphatic drainage for an area and so tumour cells initially collect in local lymph nodes. Exceptions occur when the tumour cells are able to bypass local nodes, so producing "skip metastasis".
Enlargement follows - lymphadenopathy - due to tumour presence, and/or reactive follicular and T-cell hyperplasia. Blockage of a lymphatic channel can result in oedema in the region of drainage.
Prime examples of lymphatic spread are:
Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.