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Paraneoplastic syndromes

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Paraneoplastic syndromes are symptom complexes, occurring in patients with cancer, which cannot be explained by:

  • the tumour
  • metastases
  • the hormones which are normally secreted by the tissue within which the tumour arose

Paraneoplastic syndromes are seen in about 10% of patients with advanced malignant disease.

It is important to diagnose a paraneoplastic syndrome because:

  • it may be the first presentation of an occult neoplasm
  • it may pose significant clinical problems
  • it may confound diagnosis and treatment

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The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

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