This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in


Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

Metastasis describes the state of having distant spread of a malignant tumour to a site removed from its origin. Generally, the aggressiveness and size of a given tumour is directly related to its ability to metastasize. An exception is CNS gliomas which are highly invasive but rarely metastasize.

Usually, the route of metastasis is characteristic of a particular tumour and can occur via:

  • direct extension from the site of origin
  • via fluid-filled spaces
  • through lymphatic spread
  • by traversing blood vessels and then haematogenous dissemination

Related pages

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.