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Hypervolaemic hyponatraemia

Authoring team

  • clinically detectable increased ECF volume plus hyponatraemia - generally reflects hypervolaemia from some degree of body Na+ excess
  • hyponatraemia with ECF volume excess can arise in a variety of diseases
    • causes of hypervolaemic hyponatraemia include:
      • CHF
      • liver cirrhosis
      • nephrotic syndrome
      • renal failure
      • excessive water intake
    • volume excess is generally diagnosed clinically from the history, physical examination and laboratory results
      • patients with clinical signs of volume overload (subcutaneous oedema, ascites, pulmonary oedema)
        • should be considered to have hypervolaemia unless there are alternative explanations for these findings

Reference:

  • (1) hyponatraemia Treatment Guidelines 2007: Expert Panel Recommendations The American Journal of Medicine 2007; 120 (11);S1:S1-S21.

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