You can view 5 more pages before signing in

Atkins et al. (1972)

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

This study addressed radical mastectomy against 'extended tylectomy' - a form of conservative breast treatment. Both groups had radiotherapy to regional nodes. The conservative group had radiotherapy to the residual breast tissue. The study group were women greater than 50 years of age with clinical stage I or II disease.

The conservative group had a higher incidence of local recurrence. However, this did not influence survival for stage I disease. Stage II disease had worse survival figures than for mastectomy.

The study was flawed in that the dose of radiotherapy was suboptimal.

Reference:

Atkins, H., Hayward, J.L., Klugman, D.J., Wayte, A.B.; "Treatment of early breast cancer: a report after ten years of a clinical trial." BMJ, 1972; 2: 423-429.

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.