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Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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  • in England,obstetric cholestasis (also referred to as intrahepatic cholestasis of pregnancy) affects 0.7% of pregnancies in multiethnic populations and 1.2–1.5% of women of Indian–Asian or Pakistani–Asian origin
  • prevalence is influenced by genetic and environmental factors and varies between populations worldwide
    • for example, in Chile,2.4% of all pregnancies are affected,with a 5% prevalence in women of Araucanian–Indian origin


  1. Walker KF et al. Pharmacological interventions for treating intrahepatic cholestasis of pregnancy. Cochrane Database of Systematic Reviews 2020, Issue 7. Art. No.: CD000493. DOI: 10.1002/14651858.CD000493.pub3.
  2. Royal College of Obstetricians and Gynaecologists (April 2011). Guideline No. 43 - Obstetric cholestasis.

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