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Efficacy

Authoring team

The efficacy of orlistat has been demonstrated in various contexts including:

  • simple obesity
  • obese patients with type II diabetes
  • adolescent obesity

Orlistat significantly increases weight loss compared to placebo but its effectiveness is limited by its side-effects. Clinical trials suggest a moderate weight loss compared to placebo - about 2-5 kg over a year.

Reference

  1. Carter R, Mouralidarane A, Ray S, et al. Recent advancements in drug treatment of obesity. Clin Med. 2012 Oct;12(5):456-60

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