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Differential diagnosis of histopathological findings

Authoring team

Total villous atrophy:

  • coeliac disease
  • idiopathic mucosal atrophy
  • cow's milk intolerance
  • soy protein intolerance
  • severe malnutrition
  • tropical sprue

Subtotal villous atrophy:

  • bacterial overgrowth
  • intestinal ischaemia
  • Zollinger-Ellison syndrome
  • dermatitis herpetiformis
  • partially treated Crohn's disease

Non-villous abnormality:

  • lymphoma
  • Whipple's disease
  • abetalipoproteinaemia
  • radiation enteritis
  • giardiasis
  • lymphangiectasia

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