This site is intended for healthcare professionals

Sign in
Go to /sign-in page

You can view 5 more pages before signing in

Onset of action of SSRIs

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

Authoring team

  • a systematic review revealed that treatment with selective serotonin reuptake inhibitors (SSRIs) is associated with symptomatic improvement in depression by the end of the first week of use, and the improvement continues at a decreasing rate for at least 6 weeks
    • this study specifically evaluated the effects of SSRIs at one week with that of placebo - the analysis found that effects at one week were true drug effects
      • analysis included studies of 6 commonly used SSRIs: escitalopram, citalopram, fluoxetine, fluvoxamine, paroxetine and sertraline

Reference:

  1. Taylor MJ et al.Early onset of selective serotonin reuptake inhibitor antidepressant action: systematic review and meta-analysis. Arch Gen Psychiatry. 2006 Nov;63(11):1217-23

Create an account to add page annotations

Create a free account

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.