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Prevention of dementia

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Prevention of dementia

Prevention of dementia is hugely beneficial for a large number of individuals as well as on the society as a whole

  • prevention could be:
    • primary prevention - to prevent early pathological changes of dementia
    • secondary prevention - to delay the pathological process
  • even a delay in the onset of disease can be regarded as a preventive strategy since there is evidence of the prevalence decreasing by half when the onset is delayed by 5 years
  • a knowledge about dementia risk factors is necessary for the preventive strategies
  • early identification of the disease will lead to early interventions in secondary prevention

In patients with risk factors the following steps could be undertaken

  • vascular and other modifiable risk factors (e.g. - smoking, excessive alcohol intake, obesity, DM) in middle-aged and older people should be reassessed and treated if necessary
  • refer the patient for genetic counseling along with their unaffected relatives with a likely genetic cause for dementia e.g. - familial autosomal dominant AD
  • people with signs of MCI should be referred for assessment by memory assessment services to identify dementia early

The following interventions are not recommended for primary prevention of the disease:

  • statins
  • hormone replacement therapy
  • vitamin E
  • non-steroidal anti-inflammatory drugs

Reference:


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