This site is intended for healthcare professionals

Go to /sign-in page

You can view 5 more pages before signing in

Clinical features

Authoring team

There is a gradually progressive spastic weakness of the legs with increasing difficulties with walking.

The tendon reflexes are brisk in the legs with extensor plantar responses.

If onset is during childhood then pes cavus is common.

More extensive disease may affect the arms and the sphincters.

Complicated hereditary spastic paraplegia is associated with:

  • cerebellar ataxia and dysarthria
  • optic atrophy and pigmentary macular degeneration
  • sensorimotor polyneuropathy
  • epilepsy
  • ichthyosis
  • dementia

Create an account to add page annotations

Annotations allow you to add information to this page that would be handy to have on hand during a consultation. E.g. a website or number. This information will always show when you visit this page.

The content herein is provided for informational purposes and does not replace the need to apply professional clinical judgement when diagnosing or treating any medical condition. A licensed medical practitioner should be consulted for diagnosis and treatment of any and all medical conditions.

Connect

Copyright 2024 Oxbridge Solutions Limited, a subsidiary of OmniaMed Communications Limited. All rights reserved. Any distribution or duplication of the information contained herein is strictly prohibited. Oxbridge Solutions receives funding from advertising but maintains editorial independence.