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Interhemispheric disconnection

Last reviewed dd mmm yyyy. Last edited dd mmm yyyy

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Interhemispheric disconnection describes lesions of the corpus callosum linking related parts of the two hemispheres.

Presentations:

  • left side apraxia - lesion of anterior corpus callosum with interruption of the connections between left and right association motor cortices. Characterised by apraxia of left sided limb movements.
  • pure word blindness - lesion of posterior corpus callosum and dominant occipital lobe with interruption of connections between the visual cortex and the angular gyrus - Wernicke's area. Characterised by inability to read, to name colours and to copy writing.
  • agenesis of corpus callosum - no connection between the two hemispheres. Characterised by inability to name an object presented visually or by touch to the non-dominant hemisphere.

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