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Late features

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Initially the limbs are weak and flaccid. Typically muscles are pseudohypertrophic in late disease (1).

Later fibrous contractures occur in the muscles which antagonise the more severely affected groups. Contractures are seen in:

  • ankle plantar-flexors
  • hamstrings
  • hip flexors

Tendon reflexes are lost.

Bones become osteoporotic.

Reference:

  1. Personal Communication. Stephen Meech (MBBS, GP) Committee member - Duchenne Family Support Group (March 2006).

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