Localisation of cerebellar lesions
Cerebellar disease may be the result of lesions which affect:
- the cerebellum
- the input from proprioceptors, inner ear and cerebral hemispheres
- the output from the cerebellum, which passes via the superior cerebellar peduncles
The clinical features of lesions in different locations is outlined below:
Midline cerebellar lesions affect:
- anti-gravity reflexes
- gait and stance ataxia
- little limb ataxia
Lesions in the superior cerebellar peduncle (outflow lesions) cause:
- intention tremor
Lesions in the midbrain, pons and medulla (inflow & outflow lesions) cause:
- ataxia and/or intention tremor
- other localising brainstem signs e.g. cranial nerve palsies
Ref: Essential Neurology, Wilkinson, I.M.S., 1993, 2nd edition, Blackwell Scientific Publications, p.114
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